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Leading technology and global reputation
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Decibel, Principal Scientist
“A lot of our programs internally have been having great results with the AAV vectors you all have been packaging. PackGene is rapidly becoming our go-to for AAV vectors! ”
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Biogen Scientist
“I have spreaded the word of my satisfaction with your AAV vectors to many people in Biogen’s research labs and I hope we continue to be a regular customer in the future.”
Learn More About Us
![Citation Citation](https://static.packgene.com/wp-content/uploads/2024/07/Citation.png)
PCDH15 Dual-AAV Gene Therapy for Deafness and Blindness in Usher Syndrome Type 1F
BioRxiv. 2023 Nov 13 Maryna V. Ivanchenko, Daniel M. Hathaway, Eric M. Mulhall, Kevin T. Booth, Mantian Wang, Cole W. Peters, Alex J. Klein, Xinlan Chen, Yaqiao Li, Bence György and David P. Corey Products used in the paper Details Operation AAV vector AAVs were...
Optimization of base editors for the functional correction of SMN2 as a treatment for spinal muscular atrophy
Nature Biomedical Engineering. 2023 Dec 6 Christiano R. R. Alves, Leillani L. Ha, Rebecca Yaworski, Emma R. Sutton, Cicera R. Lazzarotto, Kathleen A. Christie, Aoife Reilly, Ariane Beauvais, Roman M. Doll, Demitri de la Cruz, Casey A. Maguire, Kathryn J. Swoboda,...
Intranasal mask for protecting the respiratory tract against viral aerosols
Nature Communications. 2023 Dec 18 Xiaoming Hu, Shuang Wang, Shaotong Fu, Meng Qin, Chengliang Lyu, Zhaowen Ding, Yan Wang, Yishu Wang, Dongshu Wang, Li Zhu, Tao Jiang, Jing Sun, Hui Ding, Jie Wu, Lingqian Chang, Yimin Cui, Xiaocong Pang, Youchun Wang, Weijin Huang,...
NeuroD1 and Ascl1 Convert Human Glial Cells into Neurons in Ex Vivo Culture of Human Brain Tissue
Research Square. 2023 Dec 14 Liang Xu, Qingsong Wang, Jiancheng Liao, Jiajun Zheng, Bing Qin, Wen Li, Jiaxuan Zhang, Wei Li, Xiangyu Wang, Maoying Zhang, Gong Chen Products used in the paper Details Operation AAV vector packaging Adeno-associated virus (AAV): AAV9...
Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair
Neuron. 2023 Dec 20 Ngan Pan Bennett Au, Tan Wu, Xinyu Chen, Feng Gao, Yuen Tung Yolanda Li, Wing Yip Tam, Kwan Ngok Yu, Daniel H. Geschwind, Giovanni Coppola, Xin Wang, and Chi Him Eddie Ma Products used in the paper Details Operation AAV vector packaging...
The Study on PLA-based nano-bio effects and its biomedical applications
. 2023 Aug DING Zhaowen Products used in the paper Details Operation was used as a negative control Request Quote Research Field: Coronavirus Keywords: PLA, nano-bio interfacial interaction, lamella nanomaterial, microsphere AAV Serotype: pseudovirus Animal or cell...
Regulation of myo-miR-24-3p on the Myogenesis and Fiber Type Transformation of Skeletal Muscle
Genes. 2024 Feb 21 Danyang Fan, Yilong Yao, Yanwen Liu, Chao Yan, Fanqinyu Li, Shilong Wang, Mei Yu, Bingkun Xie and Zhonglin Tang Products used in the paper Details Operation AAV vector packaging AAV1-hOTOF was developed by researchers at the Eye & ENT Hospital of...
Enhancing transduction efficiency of adeno-associated virus 9 by cell line engineering: implication for gene therapy potency assay
Biotechnology and Bioprocess Engineering. 2024 Feb 19 Nanyeong Go, Changhyun Ahn & Jae Young Lee Products used in the paper Details Operation AAV vector packaging In brief, mice were intranasally infected with AAV-hACE2 (PackGene Biotech, Guangzhou, China) Request...
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Webinar: Current Challenges and New Approaches to Developing rAAV Manufacturing Processes for Large-scale GMP Production
Abstract:Adeno-associated virus (AAV) production faces significant challenges, including low yields, scalability issues, and inconsistent quality. Scaling up AAV production to meet clinical and commercial demands requires innovative solutions. PackGene's proprietary...
Cell & Gene Meeting on the MESA (ARM; Phoenix, AZ, Oct 7-9)
The 2024 Cell & Gene Meeting on the Mesa is the premier annual conference for industry leaders, focused on innovative research and overcoming commercial challenges in cell and gene therapy. The event features expert panels, networking opportunities, and over 100...
Socienty for Neuroscience (Chicago, IL, Oct 5-9)
Annually, scientists from across the globe gather to explore new concepts, present their research, and experience the pinnacle of their field. By attending, you can present your own research, network with fellow scientists, participate in sessions and events, and...
CASSS-CGTP ( Rockville, MD, Jun 11-13)
The Cell and Gene Therapy Products (CGTP) Symposium focuses on Manufacturing, Quality, and Regulatory Considerations, fostering an exchange of scientific ideas and interactions with regulators that shape evolving regulatory frameworks for these innovative products....
BIO International (San Diego, Jun 3-6, 2024)
Whether you're involved in pharmaceuticals, biotech, academia, non-profits, or government, or working as a researcher, business developer, or investor, BIO is the place to establish valuable connections. The Premier Access package includes our BIO One-on-One...
Webinar: Treating Autosomal Recessive Deafness 9 with AAV1-hOTOF Gene Therapy (4/24/2024 10:00am EST/ 7:00am PST)
Abstract:Discover a groundbreaking advancement in treating Autosomal Recessive Deafness 9 (ARD9) with Dr. Yilai Shu, a pioneer in gene therapy for hearing loss. This webinar delves into the innovative AAV1-hOTOF gene therapy trial, offering new hope for individuals...
ASGCT (Maryland, May 7-11, 2024)
Abstract:Welcome to ASGCT 2024, the American Society of Gene and Cell Therapy's flagship conference. Esteemed researchers, clinicians, and industry leaders converge at this influential event to navigate the forefront of gene and cell therapy. In the vibrant atmosphere...
American Academy of Neurology (Colorado, Apri 13-18, 2024)
Abstract:The American Academy of Neurology Conference 2024 in Denver, a pivotal gathering for the brightest minds in neurology. This esteemed event brings together experts, researchers, clinicians, and innovators from around the globe to explore the forefront of...
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Exploring Tau Protein’s Role in Glaucoma: New Insights and Therapeutic Potential
Glaucoma, a chronic neurodegenerative disorder, leads to irreversible vision loss by damaging retinal ganglion cells (RGCs) and the optic nerve, often associated with increased intraocular pressure (IOP). Despite the benefits of IOP-lowering treatments, the underlying...
FDA-mandated CAR-T monitoring period could be halved, say researchers
In patients with diffuse large B-cell non-Hodgkin lymphoma (DLBCL), the two hallmark post-chimeric antigen receptor (CAR)-T therapy toxicities are extremely rare after two weeks, supporting a shorter, more flexible toxicity monitoring period, according to a study...
Ancestral CRISPR-Cas13 Ribonucleases Discovered: Implications for Genome Editing
In a pioneering study published in *Science*, a team of researchers led by Peter H. Yoon and Jennifer A. Doudna from the University of California, Berkeley, has made a remarkable discovery in the realm of CRISPR technology. The team has identified an ancestral clade...
KBI Biopharma Expands Manufacturing Contract with Global Pharmaceutical Company
KBI Biopharma Inc., a JSR Life Sciences company and global cGMP contract development and manufacturing organization (CDMO), has extended and expanded its manufacturing contract with a leading global pharmaceutical company. Originally initiated in 2020, the renewed...
Emmes Group partners with Miimansa AI to accelerate adoption of Generative AI in clinical research
Emmes Group, a leading specialty tech-enabled global contract research organization (CRO), today announced a multi-year strategic partnership with Miimansa AI. A critical pillar of the partnership, aimed at revolutionizing clinical research at Emmes, is the...
mRNA Vaccines and Therapeutics Market to Reach US$ 85.9 billion, Garnering a 14.6% CAGR by 2034: Transparency Market Research Inc.
Besides vaccines, mRNA technology is being explored for therapeutic applications in oncology, infectious diseases, genetic disorders, and other areas. This diversification expands the market potential. The mRNA vaccines and therapeutics market was projected to attain...
Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus
Huntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallographic purposes. Credit: Public domainIn Huntington's disease, the mutant huntingtin gene (HTT)...
Agilent Technologies to acquire CDMO Biovectra for $925M
Agilent Technologies plans to buy Canadian CDMO Biovectra in a $925 million deal, which Agilent says will deepen its focus on oligonucleotides and CRISPR. Biovectra says it has fill-finish services, pDNA and mRNA capabilities, lipid nanoparticle formulation and...
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